Synaptic, transcriptional and chromatin genes disrupted in autism Associated with Submicroscopic 21q22 Deletion Including DYRK1A October 30, 2014 DYRK1A Read Full Read more
Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing October 28, 2014 DYRK1A Read Full Read more
DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease. June 12, 2014 DYRK1A Read Full Read more
Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage May 4, 2014 DYRK1A Read Abstract Read more
Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass. January 30, 2014 DYRK1A Read Abstract Read more
A de novo 1.4-Mb deletion at 21q22.11 in a boy with developmental delay January 23, 2014 DYRK1A Read Abstract Read more
Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors January 1, 2014 DYRK1A Read Abstract Read more
Clinical Whole-Exome Sequencing for the Diagnosis of Mendelian Disorders October 17, 2013 DYRK1A Read Full Read more
Dosage of Dyrk1a Shifts Cells within a p21-Cyclin D1 Signaling Map to Control the Decision to Enter the Cell Cycle September 9, 2013 DYRK1A Read Full Read more
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth. May 1, 2013 DYRK1A Read Full Read more
Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disord December 1, 2012 DYRK1A Read Full Read more
The DYRK1A gene is a cause of syndromic intellectual disability with severe microcephaly and epilepsy October 25, 2012 DYRK1A Read Abstract Read more
Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice. August 26, 2012 DYRK1A Read Abstract Read more
Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals August 2, 2012 DYRK1A Read Full Read more
De Novo Gene Disruptions in Children on the Autistic Spectrum April 26, 2012 DYRK1A Read Full Read more
DYRK1A: a master regulatory protein controlling brain growth. January 26, 2012 DYRK1A Read Abstract Read more
Phosphorylation of Munc18-1 by DYRK1A regulates its interaction with Syntaxin 1 and X11a January 1, 2012 DYRK1A Read Full Read more
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling March 30, 2011 DYRK1A Read Full Read more
Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly March 1, 2011 DYRK1A Read Abstract Read more
Distinctive Phenotypic Abnormalities Associated with Submicroscopic 21q22 Deletion Including DYRK1A September 14, 2010 DYRK1A Read Full Read more
