Characterizing autism spectrum disorders by key biochemical pathways September 24, 2015 DYRK1A Read Full Read more
The Kinase DYRK1A Reciprocally Regulates the Differentiation of Th17 and Regulatory T Cells May 22, 2015 Amy Clugston Read Full / Video Presentation Read more
Dyrk1A Phosphorylates Parkin at Ser-131 and Negatively Regulates its Ubiquitin E3 Ligase Activity. May 12, 2015 DYRK1A Read Full Read more
DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies. May 12, 2015 DYRK1A Read Full Read more
Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A April 29, 2015 DYRK1A Read Full Read more
Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID. February 24, 2015 DYRK1A Read Full Read more
Synaptic, transcriptional and chromatin genes disrupted in autism Associated with Submicroscopic 21q22 Deletion Including DYRK1A October 30, 2014 DYRK1A Read Full Read more
Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing October 28, 2014 DYRK1A Read Full Read more
DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease. June 12, 2014 DYRK1A Read Full Read more
Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage May 4, 2014 DYRK1A Read Abstract Read more
Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass. January 30, 2014 DYRK1A Read Abstract Read more
A de novo 1.4-Mb deletion at 21q22.11 in a boy with developmental delay January 23, 2014 DYRK1A Read Abstract Read more
Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors January 1, 2014 DYRK1A Read Abstract Read more
Clinical Whole-Exome Sequencing for the Diagnosis of Mendelian Disorders October 17, 2013 DYRK1A Read Full Read more
Dosage of Dyrk1a Shifts Cells within a p21-Cyclin D1 Signaling Map to Control the Decision to Enter the Cell Cycle September 9, 2013 DYRK1A Read Full Read more
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth. May 1, 2013 DYRK1A Read Full Read more
Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disord December 1, 2012 DYRK1A Read Full Read more
The DYRK1A gene is a cause of syndromic intellectual disability with severe microcephaly and epilepsy October 25, 2012 DYRK1A Read Abstract Read more
Dyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice. August 26, 2012 DYRK1A Read Abstract Read more
