Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals August 2, 2012 DYRK1A Read Full Read more
De Novo Gene Disruptions in Children on the Autistic Spectrum April 26, 2012 DYRK1A Read Full Read more
DYRK1A: a master regulatory protein controlling brain growth. January 26, 2012 DYRK1A Read Abstract Read more
Phosphorylation of Munc18-1 by DYRK1A regulates its interaction with Syntaxin 1 and X11a January 1, 2012 DYRK1A Read Full Read more
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling March 30, 2011 DYRK1A Read Full Read more
Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly March 1, 2011 DYRK1A Read Abstract Read more
Distinctive Phenotypic Abnormalities Associated with Submicroscopic 21q22 Deletion Including DYRK1A September 14, 2010 DYRK1A Read Full Read more
Function and regulation of DYRK1A: towards understanding down syndrome August 14, 2009 DYRK1A Read Abstract Read more
Impaired Spatial Learning Strategies and Novel Object Recognition in Mice Haploinsufficient for the Dual Specificity Tyrosine-Regulated Kinase-1A (Dyrk1A) July 1, 2008 DYRK1A Read Full Read more
Truncation of the Down Syndrome Candidate Gene DYRK1A in Two Unrelated Patients with Microcephaly May 1, 2008 DYRK1A Read Full Read more
DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects February 7, 2006 DYRK1A Read Abstract Read more
DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1. May 13, 2005 DYRK1A Read Full Read more
DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly April 14, 2003 DYRK1A Read Full Read more
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice. September 1, 2002 DYRK1A Read Full Read more
Possible narrowed assignment of the loci of monosomy 21-associated microcephaly and intrauterine growth retardation to a 1.2-Mb segment at 21q22.2. January 1, 1997 DYRK1A Read Full Read more
A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region June 16, 1996 DYRK1A Read Abstract Read more
